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var(--c-line);white-space:nowrap;font-size:.76rem;font-weight:700}.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] th[data-astro-cid-ikooipj4][scope=row]{text-align:left;font-family:var(--ff-display);color:var(--c-ink);padding:var(--s-4);vertical-align:top;white-space:nowrap;font-size:.98rem;font-weight:700}.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] td[data-astro-cid-ikooipj4]{padding:var(--s-4);color:var(--c-text-2);vertical-align:top}.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] tr[data-astro-cid-ikooipj4]+tr[data-astro-cid-ikooipj4] th[data-astro-cid-ikooipj4][scope=row],.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] tr[data-astro-cid-ikooipj4]+tr[data-astro-cid-ikooipj4] td[data-astro-cid-ikooipj4]{border-top:1px solid var(--c-line)}.marker-table[data-astro-cid-ikooipj4] .marker-row-accent[data-astro-cid-ikooipj4] th[data-astro-cid-ikooipj4][scope=row],.marker-table[data-astro-cid-ikooipj4] .marker-row-accent[data-astro-cid-ikooipj4] td[data-astro-cid-ikooipj4]{background:var(--c-accent-soft);color:var(--c-ink)}.marker-table[data-astro-cid-ikooipj4] .marker-row-accent[data-astro-cid-ikooipj4] th[data-astro-cid-ikooipj4][scope=row]{color:var(--c-accent-darker)}.marker-panel-note[data-astro-cid-ikooipj4]{color:var(--c-text-2);background:color-mix(in srgb, var(--c-bone-lightest) 78%, transparent);border-left:4px solid var(--c-accent);padding:var(--s-4) var(--s-5);border-radius:0 var(--r-md) var(--r-md) 0;max-width:1040px;margin:var(--s-6) auto 0;font-size:.95rem;line-height:1.65}.marker-panel-note[data-astro-cid-ikooipj4] strong[data-astro-cid-ikooipj4]{color:var(--c-ink);font-weight:600}.boundary-block[data-astro-cid-ikooipj4]{align-items:center}.boundary-section[data-astro-cid-ikooipj4]{padding-bottom:clamp(2rem,3.5vw,3rem)}.boundary-note[data-astro-cid-ikooipj4]{border-left:4px solid var(--c-accent);padding:var(--s-5) var(--s-6);border-radius:0 var(--r-md) var(--r-md) 0;background:color-mix(in srgb, var(--c-bone-lightest) 78%, transparent)}@media (width<=980px){.biomarker-hero[data-astro-cid-ikooipj4]{padding-block:calc(4.25rem + var(--s-10)) var(--s-8)}.hero-grid[data-astro-cid-ikooipj4],.split-block[data-astro-cid-ikooipj4],.intro-block[data-astro-cid-ikooipj4] .split-block[data-astro-cid-ikooipj4]{grid-template-columns:1fr}.hero-copy[data-astro-cid-ikooipj4]{max-width:680px}}@media (width<=640px){.block-center[data-astro-cid-ikooipj4]{padding-block:var(--s-12)}.section-head[data-astro-cid-ikooipj4]{text-align:left;margin-bottom:var(--s-8)}.section-head-left[data-astro-cid-ikooipj4]{margin-bottom:var(--s-6)}.section-head[data-astro-cid-ikooipj4] p[data-astro-cid-ikooipj4]{margin-inline:0}.marker-context-head[data-astro-cid-ikooipj4]{gap:var(--s-4);margin-bottom:var(--s-6);grid-template-columns:1fr}.marker-context-head[data-astro-cid-ikooipj4] 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tr[data-astro-cid-ikooipj4]:last-child{border-bottom:0}.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] th[data-astro-cid-ikooipj4][scope=row],.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] td[data-astro-cid-ikooipj4]{white-space:normal;border:0;padding:0}.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] th[data-astro-cid-ikooipj4][scope=row]{margin:0 0 var(--s-3);font-size:1.02rem}.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] td[data-astro-cid-ikooipj4]{margin:var(--s-3) 0 0;font-size:.9rem}.marker-table[data-astro-cid-ikooipj4] tbody[data-astro-cid-ikooipj4] td[data-astro-cid-ikooipj4]:before{content:attr(data-label);margin:0 0 var(--s-1);font-family:var(--ff-mono);color:var(--c-text-3);text-transform:uppercase;letter-spacing:.04em;font-size:.68rem;font-weight:700;display:block}.marker-table[data-astro-cid-ikooipj4] .marker-row-accent[data-astro-cid-ikooipj4] th[data-astro-cid-ikooipj4][scope=row],.marker-table[data-astro-cid-ikooipj4] .marker-row-accent[data-astro-cid-ikooipj4] td[data-astro-cid-ikooipj4]{background:0 0}.boundary-note[data-astro-cid-ikooipj4]{padding:var(--s-4)}}